If you love the robust, savory taste of an Italian sub but are avoiding bread, these Keto Italian Sub Roll-Ups are an ideal, low-carb alternative. Thin layers of genoa salami, pepperoni, ham, and provolone are rolled around diced roma tomato and crisp red onion, finished with a sprinkle of oregano for that classic Italian flavor. They’re easy to assemble, portable, and perfect for snacks, appetizers, or meal prep.

I developed this recipe when I wanted all the deli flavors of a favorite sandwich without the carbs. These roll-ups came together during a quick fridge clean-out and instantly became a go-to snack. They require no cooking, come together in about 15 minutes, and deliver the same salty, tangy, and cheesy satisfaction of an Italian sub in a single bite.
These roll-ups are ideal for busy schedules. Make a batch in the morning or the night before and stash them in the fridge for grab-and-go snacks all week. They’re filling enough to keep you on track with keto goals and versatile enough to suit different tastes—swap cheeses or add a little heat if you like.
Below you’ll find clear instructions, ingredient quantities, and practical tips for getting tight, uniform rolls. Use the variations to customize the recipe to what you have on hand or to match dietary preferences. Enjoy!
How to Make Keto Italian Sub Roll-Ups
Ingredients You’ll Need For This Recipe

- 12 slices genoa salami
- 12 slices sandwich pepperoni
- 12 slices thin-sliced ham
- 12 slices provolone cheese
- 2 teaspoons dried oregano
- 1 roma tomato, diced small
- ¼ cup red onion, diced small
Step By Step Instructions
- On a tray or baking sheet, arrange the meat and cheese in a vertical chain. Layer in this order from bottom to top: salami, pepperoni, provolone, ham. Leave about ½ to 1 inch between each stack so you can roll easily.

- Near the bottom edge of the ham layer, sprinkle a pinch of oregano, then add a small spoonful of the diced roma tomato and a little diced red onion. Keep the filling centered and light so the roll holds together.



- Starting from the bottom, roll the ham tightly upward and continue rolling until you reach the top of the salami. Aim for a firm roll so the ingredients stay inside. Secure each roll with a toothpick if needed.

- Serve immediately or cover and refrigerate until ready to serve. These keep well for several days and make a convenient snack or party appetizer.
Tips and Tricks
- Keep it tight: Roll firmly from the bottom to compact the fillings and help the roll keep its shape. Use additional toothpicks for looser rolls.
- Prep ahead: Assemble the rolls the night before and store them in an airtight container. Chilling helps the flavors meld and makes slicing or serving easier.
- Customize fillings: Swap provolone for mozzarella or Swiss, replace red onion with banana peppers for tang, or add a small drizzle of Italian dressing or a pinch of red pepper flakes if you want extra flavor.
- Portion control: These roll-ups are naturally portioned; one or two make a satisfying snack. For parties, place them on a platter with skewers for easy serving.
If you enjoyed this recipe, here are a few other keto-friendly snack ideas to try (titles only):
- 25 Genius Quick & Easy 2-Minute Keto Snack Ideas
- Keto Chicken Bacon Ranch Bites
- Air Fryer Crispy Carnivore Cream Cheese Bites
- Keto Pepperoni Cream Cheese Bites
PIN FOR LATER!

Recipe

Keto Italian Sub Roll-Ups
Author: Olivia Wyles
Prep: 15 mins | Total: 15 mins
Course: Appetizer, Snack | Cuisine: American, Italian
Servings: 12 roll-ups
Ingredients
- 12 slices genoa salami
- 12 slices sandwich pepperoni
- 12 slices ham, thin sliced
- 12 slices provolone
- 2 teaspoons oregano
- 1 roma tomato, diced small
- ¼ cup red onion, diced small
Instructions
- Arrange the salami, pepperoni, provolone, and ham in vertical stacks on a tray, leaving ½–1 inch between each stack.
- Near the bottom of each ham slice, sprinkle oregano and add a small amount of diced tomato and red onion.
- Roll tightly from the bottom up to the top of the salami, then secure with a toothpick if needed.
- Serve immediately or cover and refrigerate until ready to serve.
Nutrition
Serving: 67 g | Calories: 151.9 kcal (8%)
Carbohydrates: 1.38 g | Net Carbs: 1.26 g
Protein: 12.36 g (25%) | Fat: 10.73 g (17%)
Fiber: 0.11 g
Keywords: Keto Italian Sub Roll-Ups
Did you love this recipe? Leave a rating or review to help others find it and to share your experience.